Scientists at Caltech have used 4D electron microscopy to visualize the biomechanics of DNA.
DNA was made to vibrate with a laser pulse and then probed with electron pulses to observe the specimen in space and time, revealing the natural resonant frequency. With selective nanocutting, it was possible to determine the stiffness of the DNA filament at different points.
Pictures and a summary of the research are available from Caltech, along with details of the 4D electron microscope.