Striatal dopamine is increased by virtually all drugs of abuse, including alcohol. Scientists using positron emission tomography were able to show that, even without alcohol, the flavour of beer can induce dopamine release.
Forty-nine men – ranging from social to heavy drinkers, with a varied family history of alcoholism – underwent two PET scans: one while tasting beer, and one while tasting Gatorade. Relative to the control flavour of Gatorade, beer flavour increased self-reported desire to drink and induced dopamine release.
The results demonstrate that alcohol-conditioned flavour cues can provoke ventral striatal dopamine release, and that the response is strongest in subjects with a greater genetic risk for alcoholism.