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Scientists have found that a mutation in the gene encoding casein kinase Iδ (CKIδ) is associated with both the presence of migraine and advanced sleep phase. The resulting alterations (T44A and H46R) caused reduced enzyme activity.

Results of experiments on mice suggest that decreases in CKIδ activity can contribute to the development of migraine.

A new study has shown that lightning triggers headaches in people who suffer from migraines.

The researchers used daily headache diaries from 90 patients in two previous clinical trials that were conducted in Cincinnati and St Louis, combined with data from sensors that detect electromagnetic radiation and can identify cloud-to-ground lightning strikes with 90% efficiency and determine the location of lightning strikes within 500 meters.